outcomes of amniotic membrane grafting in surgery for severe upper lid cicatricial entropion

نویسندگان

احمد علی فردوسی

aa ferdosi تهران- پاسداران- خیابان امیر ابراهیمی- نبش بوستان نهم- پلاک 5- مرکز تحقیقات چشم هیوا پارسافر

h parsafar تهران- پاسداران- خیابان امیر ابراهیمی- نبش بوستان نهم- پلاک 5- مرکز تحقیقات چشم مهدی یاسری

m yaseri دانشگاه علوم پزشکی تهران مریم فردوسی

m ferdosi

چکیده

purpose: to evaluate the efficacy of amniotic membrane (am) grafting in surgery for severe upper lid cicatricial entropion. methods: this randomized clinical trial was performed on both upper eyelids of 22 patients with severe cicatricial entropion. on one side the anterior and posterior lamellae were split and the anterior lamella was recessed. on the other side, the same procedure was done but bare tarsus was covered with am. patients were evaluated one day, one and two weeks, and one and three months after surgery. the mean follow-up period was 9.89 ± 6.17 (range 4-21) months. results: overall, 22 patients (13 women and 9 men) aged 55 to 84 years (mean age, 71.54±8.58) entered the study. the cause of cicatricial entropion was old trachoma in 18 (81.8%) and idiopathic in 4 (18.2%) subjects. in second week, eyelids with am stained less with fluorescein than the control group (p= 0.016). at the end of the first month, all lids were epithelialized. there was no significant difference between the two groups in the number of lids with recurrent trichiasis but the number of lashes in contact with the globe in the am group was significantly lower than the controls (p= 0.042). there was no significant difference in tarsal shrinkage and normalization of bare tarsus between the study groups. subgraft hemorrhage occurred in 3 cases in the first week which completely resolved by one month. conclusion: am is a useful tissue which can enhance reepithelialization of bare tarsus and may be considered as an adjunct in lid split entropion surgery.

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جلد ۱۴، شماره ۴، صفحات ۴۰۶-۴۱۲

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